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Serologic Markers of Autism Spectrum Disorder.
Khramova, T V; Kaysheva, Anna L; Ivanov, Y D; Pleshakova, T O; Iourov, I Y; Vorsanova, S G; Yurov, Y B; Schetkin, A A; Archakov, A I.
Affiliation
  • Khramova TV; Udmurt State University, Universitetskaya st 1, Izhevsk, Russia.
  • Kaysheva AL; V.N.Orekhovich Research Institute of Biomedical Chemistry, 10, Pogodinskaya st, Moscow, Russia, 119121. kaysheva1@gmail.com.
  • Ivanov YD; V.N.Orekhovich Research Institute of Biomedical Chemistry, 10, Pogodinskaya st, Moscow, Russia, 119121.
  • Pleshakova TO; V.N.Orekhovich Research Institute of Biomedical Chemistry, 10, Pogodinskaya st, Moscow, Russia, 119121.
  • Iourov IY; Mental Health Research Centre, Kashirskoe shosse, 34, Moscow, Russia.
  • Vorsanova SG; Separated Structural Unit "Clinical Research Institute of Pediatrics at Pirogov Russian National Research Medical University Named After Y.E Veltishev", Ministry of Health of Russian Federation, Taldomskaya 2, Moscow, Russia.
  • Yurov YB; Mental Health Research Centre, Kashirskoe shosse, 34, Moscow, Russia.
  • Schetkin AA; Center for Medical Preventive Action, Navaginskaya st 9, Sochi, Russia.
  • Archakov AI; V.N.Orekhovich Research Institute of Biomedical Chemistry, 10, Pogodinskaya st, Moscow, Russia, 119121.
J Mol Neurosci ; 62(3-4): 420-429, 2017 Aug.
Article in En | MEDLINE | ID: mdl-28730336
ABSTRACT
According to WHO data, about 67 million people worldwide are affected by autism, and this number grows by 14% annually. Among the possible causes of autism are genetic modifications, organic lesions of the central nervous system, metabolic disorders, influence of viral and bacterial infections, chemical influence to the mother's body during pregnancy, etc. The conducted research shows that research papers published until today do not name any potential protein markers that meet the requirements of the basic parameters for evaluating the efficiency of disease diagnostics, in particular high sensitivity, specificity, and accuracy. Conducting proteomic research on a big scale in order to detect serologic markers of protein nature associated with development of autism spectrum disorders seems to be highly relevant.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autism Spectrum Disorder Limits: Humans Language: En Journal: J Mol Neurosci Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2017 Document type: Article Affiliation country: RUSSIA
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Autism Spectrum Disorder Limits: Humans Language: En Journal: J Mol Neurosci Journal subject: BIOLOGIA MOLECULAR / NEUROLOGIA Year: 2017 Document type: Article Affiliation country: RUSSIA