Mitochondrial Fission Inhibitors Suppress Endothelin-1-Induced Artery Constriction.

Chen, Chang; Gao, Jin-Lai; Liu, Ming-Yu; Li, Shan-Liang; Xuan, Xiu-Chen; Zhang, Xin-Zi; Zhang, Xi-Yue; Wei, Yuan-Yuan; Zhen, Chang-Lin; Jin, Jing; Shen, Xin; Dong, De-Li

Chen, Chang; Gao, Jin-Lai; Liu, Ming-Yu; Li, Shan-Liang; Xuan, Xiu-Chen; Zhang, Xin-Zi; Zhang, Xi-Yue; Wei, Yuan-Yuan; Zhen, Chang-Lin; Jin, Jing; Shen, Xin; Dong, De-Li.

Cell Physiol Biochem ; 42(5): 1802-1811, 2017.

Article in En | MEDLINE | ID: mdl-28750371

Subject(s)

Aorta, Thoracic/physiology; Endothelin-1/metabolism; Mesenteric Arteries/physiology; Mitochondrial Dynamics/drug effects; Quinazolinones/pharmacology; Amides/pharmacology; Animals; Aorta, Thoracic/cytology; Aorta, Thoracic/drug effects; Dynamins/antagonists & inhibitors; Dynamins/metabolism; Endothelin-1/antagonists & inhibitors; Hydrazones/pharmacology; Male; Mesenteric Arteries/drug effects; Microscopy, Electron, Transmission; Mitochondria/pathology; Myocytes, Smooth Muscle/drug effects; Myocytes, Smooth Muscle/metabolism; Pyridines/pharmacology; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species/metabolism; Vasoconstriction/drug effects

Key words

Endothelin-1; Mdivi-1; Mitochondrial fission; Vascular smooth muscle

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aorta, Thoracic / Endothelin-1 / Quinazolinones / Mitochondrial Dynamics / Mesenteric Arteries Limits: Animals Language: En Journal: Cell Physiol Biochem Journal subject: BIOQUIMICA / FARMACOLOGIA Year: 2017 Document type: Article Country of publication: Germany

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