Modelling and simulation of flow and agglomeration in deep veins valves using discrete multi physics.
Comput Biol Med
; 89: 96-103, 2017 10 01.
Article
in En
| MEDLINE
| ID: mdl-28797741
ABSTRACT
The hemodynamics in flexible deep veins valves is modelled by means of discrete multi-physics and an agglomeration algorithm is implemented to account for blood accrual in the flow. Computer simulations of a number of valves typologies are carried out. The results show that the rigidity and the length of the valve leaflets play a crucial role on both mechanical stress and stagnation in the flow. Rigid and short membranes may be inefficient in preventing blood reflux, but reduce the volume of stagnant blood potentially lowering the chances of thrombosis. Additionally, we also show that in venous valves, cell agglomeration is driven by stagnation rather than mechanical stress.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Stress, Mechanical
/
Computer Simulation
/
Venous Thrombosis
/
Venous Valves
/
Hemodynamics
/
Models, Cardiovascular
Limits:
Humans
Language:
En
Journal:
Comput Biol Med
Year:
2017
Document type:
Article