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Protein O-mannosylation deficiency increases LprG-associated lipoarabinomannan release by Mycobacterium tuberculosis and enhances the TLR2-associated inflammatory response.
Alonso, Henar; Parra, Julien; Malaga, Wladimir; Payros, Delphine; Liu, Chia-Fang; Berrone, Céline; Robert, Camille; Meunier, Etienne; Burlet-Schiltz, Odile; Rivière, Michel; Guilhot, Christophe.
Affiliation
  • Alonso H; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.
  • Parra J; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.
  • Malaga W; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.
  • Payros D; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.
  • Liu CF; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.
  • Berrone C; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.
  • Robert C; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.
  • Meunier E; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.
  • Burlet-Schiltz O; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France.
  • Rivière M; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France. Michel.Riviere@ipbs.fr.
  • Guilhot C; Institut de Pharmacologie et de Biologie Structurale, IPBS, Université de Toulouse, CNRS, UPS, Toulouse, France. Christophe.Guilhot@ipbs.fr.
Sci Rep ; 7(1): 7913, 2017 08 11.
Article in En | MEDLINE | ID: mdl-28801649
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Lipopolysaccharides / Virulence Factors / Toll-Like Receptor 2 / Inflammation / Mannose / Mycobacterium tuberculosis Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: France
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bacterial Proteins / Lipopolysaccharides / Virulence Factors / Toll-Like Receptor 2 / Inflammation / Mannose / Mycobacterium tuberculosis Type of study: Risk_factors_studies Limits: Animals Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: France