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ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways.
Le, Thuc M; Poddar, Soumya; Capri, Joseph R; Abt, Evan R; Kim, Woosuk; Wei, Liu; Uong, Nhu T; Cheng, Chloe M; Braas, Daniel; Nikanjam, Mina; Rix, Peter; Merkurjev, Daria; Zaretsky, Jesse; Kornblum, Harley I; Ribas, Antoni; Herschman, Harvey R; Whitelegge, Julian; Faull, Kym F; Donahue, Timothy R; Czernin, Johannes; Radu, Caius G.
Affiliation
  • Le TM; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Poddar S; Ahmanson Translational Imaging Division, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Capri JR; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Abt ER; Ahmanson Translational Imaging Division, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Kim W; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Wei L; Ahmanson Translational Imaging Division, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Uong NT; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Cheng CM; Ahmanson Translational Imaging Division, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Braas D; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Nikanjam M; Ahmanson Translational Imaging Division, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Rix P; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Merkurjev D; Ahmanson Translational Imaging Division, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Zaretsky J; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Kornblum HI; Ahmanson Translational Imaging Division, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Ribas A; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Herschman HR; Ahmanson Translational Imaging Division, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Whitelegge J; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Faull KF; UCLA Metabolomic Center, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Donahue TR; David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Czernin J; Division of Hematology-Oncology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
  • Radu CG; Vector Pharma Advisors Inc., San Diego, CA, 92130, USA.
Nat Commun ; 8(1): 241, 2017 08 14.
Article in En | MEDLINE | ID: mdl-28808226
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor Cell Lymphoblastic Leukemia-Lymphoma / Ataxia Telangiectasia Mutated Proteins / Nucleotides Limits: Animals / Female / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Precursor Cell Lymphoblastic Leukemia-Lymphoma / Ataxia Telangiectasia Mutated Proteins / Nucleotides Limits: Animals / Female / Humans Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom