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Methylome Analysis of Human Bone Marrow MSCs Reveals Extensive Age- and Culture-Induced Changes at Distal Regulatory Elements.
Pasumarthy, Kalyan K; Doni Jayavelu, Naresh; Kilpinen, Lotta; Andrus, Colin; Battle, Stephanie L; Korhonen, Matti; Lehenkari, Petri; Lund, Riikka; Laitinen, Saara; Hawkins, R David.
Affiliation
  • Pasumarthy KK; Turku Centre for Biotechnology, University of Turku, Turku 20520, Finland.
  • Doni Jayavelu N; Turku Centre for Biotechnology, University of Turku, Turku 20520, Finland; Division of Medical Genetics, Department of Medicine, Department of Genome Sciences, Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.
  • Kilpinen L; Research and Development, Medical Services, Finnish Red Cross Blood Service, Helsinki 00310, Finland.
  • Andrus C; Division of Medical Genetics, Department of Medicine, Department of Genome Sciences, Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.
  • Battle SL; Division of Medical Genetics, Department of Medicine, Department of Genome Sciences, Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA.
  • Korhonen M; Cell Therapy Services, Medical Services, Finnish Red Cross Blood Service, Helsinki 00310, Finland.
  • Lehenkari P; Institute of Clinical Medicine, Division of Surgery and Institute of Biomedicine, Department of Anatomy and Cell Biology, University of Oulu, Oulu 90014, Finland; Clinical Research Center, Department of Surgery and Intensive Care, Oulu University Hospital, Oulu 90014, Finland.
  • Lund R; Turku Centre for Biotechnology, University of Turku, Turku 20520, Finland; Åbo Akademi University, Turku 20520, Finland.
  • Laitinen S; Research and Development, Medical Services, Finnish Red Cross Blood Service, Helsinki 00310, Finland.
  • Hawkins RD; Turku Centre for Biotechnology, University of Turku, Turku 20520, Finland; Division of Medical Genetics, Department of Medicine, Department of Genome Sciences, Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA. Electronic address:
Stem Cell Reports ; 9(3): 999-1015, 2017 09 12.
Article in En | MEDLINE | ID: mdl-28844656
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow Cells / Regulatory Sequences, Nucleic Acid / DNA Methylation / Mesenchymal Stem Cells Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Humans / Middle aged Language: En Journal: Stem Cell Reports Year: 2017 Document type: Article Affiliation country: Finland Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow Cells / Regulatory Sequences, Nucleic Acid / DNA Methylation / Mesenchymal Stem Cells Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Humans / Middle aged Language: En Journal: Stem Cell Reports Year: 2017 Document type: Article Affiliation country: Finland Country of publication: United States