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Glycine-replaced derivatives of [Pro3,DLeu9]TL, a temporin L analogue: Evaluation of antimicrobial, cytotoxic and hemolytic activities.
Merlino, Francesco; Carotenuto, Alfonso; Casciaro, Bruno; Martora, Francesca; Loffredo, Maria Rosa; Di Grazia, Antonio; Yousif, Ali M; Brancaccio, Diego; Palomba, Luciana; Novellino, Ettore; Galdiero, Massimiliano; Iovene, Maria Rosaria; Mangoni, Maria L; Grieco, Paolo.
Affiliation
  • Merlino F; Department of Pharmacy, University of Naples 'Federico II', Naples, 80131, Italy.
  • Carotenuto A; Department of Pharmacy, University of Naples 'Federico II', Naples, 80131, Italy.
  • Casciaro B; Department of Biochemical Sciences, Laboratory Affiliated to Pasteur Institute Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, 00185, Italy.
  • Martora F; Department of Experimental Medicine, Università della Campania 'Luigi Vanvitelli', Naples, 80138, Italy.
  • Loffredo MR; Department of Biochemical Sciences, Laboratory Affiliated to Pasteur Institute Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, 00185, Italy.
  • Di Grazia A; Department of Biochemical Sciences, Laboratory Affiliated to Pasteur Institute Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, 00185, Italy.
  • Yousif AM; Department of Chemistry, University of Texas at Dallas, 800 W. Campbell Rd., Richardson, TX, 75080, United States.
  • Brancaccio D; Department of Pharmacy, University of Naples 'Federico II', Naples, 80131, Italy.
  • Palomba L; Department of Experimental Medicine, Università della Campania 'Luigi Vanvitelli', Naples, 80138, Italy.
  • Novellino E; Department of Pharmacy, University of Naples 'Federico II', Naples, 80131, Italy.
  • Galdiero M; Department of Experimental Medicine, Università della Campania 'Luigi Vanvitelli', Naples, 80138, Italy.
  • Iovene MR; Department of Experimental Medicine, Università della Campania 'Luigi Vanvitelli', Naples, 80138, Italy.
  • Mangoni ML; Department of Biochemical Sciences, Laboratory Affiliated to Pasteur Institute Italia-Fondazione Cenci Bolognetti, Sapienza University of Rome, Rome, 00185, Italy. Electronic address: marialuisa.mangoni@uniroma1.it.
  • Grieco P; Department of Pharmacy, University of Naples 'Federico II', Naples, 80131, Italy. Electronic address: paolo.grieco@unina.it.
Eur J Med Chem ; 139: 750-761, 2017 Oct 20.
Article in En | MEDLINE | ID: mdl-28863356
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Antimicrobial Cationic Peptides / Glycine / Anti-Bacterial Agents Limits: Adult / Humans Language: En Journal: Eur J Med Chem Year: 2017 Document type: Article Affiliation country: Italy Country of publication: France
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Antimicrobial Cationic Peptides / Glycine / Anti-Bacterial Agents Limits: Adult / Humans Language: En Journal: Eur J Med Chem Year: 2017 Document type: Article Affiliation country: Italy Country of publication: France