CFTR-NHERF2-LPA2 Complex in the Airway and Gut Epithelia.

Zhang, Weiqiang; Zhang, Zhihong; Zhang, Yanhui; Naren, Anjaparavanda P

Zhang, Weiqiang; Zhang, Zhihong; Zhang, Yanhui; Naren, Anjaparavanda P.

Affiliation

Zhang W; Department of Pediatrics & Department of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA. wzhang16@uthsc.edu.
Zhang Z; Department of Pediatrics & Department of Physiology, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA. zzhang19@uthsc.edu.
Zhang Y; Department of Bioscience research, College of Dentistry, University of Tennessee Health Science Center, Memphis, TN 38163, USA. yzhang36@uthsc.edu.
Naren AP; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA. anaren@cchmc.org.

Int J Mol Sci ; 18(9)2017 Sep 04.

Article in En | MEDLINE | ID: mdl-28869532

Subject(s)

Cystic Fibrosis Transmembrane Conductance Regulator/metabolism; Intestinal Mucosa/metabolism; Multiprotein Complexes/metabolism; Phosphoproteins/metabolism; Receptors, Lysophosphatidic Acid/metabolism; Respiratory Mucosa/metabolism; Sodium-Hydrogen Exchangers/metabolism; Animals; Cell Membrane/metabolism; Cystic Fibrosis/drug therapy; Cystic Fibrosis/genetics; Cystic Fibrosis/metabolism; Cystic Fibrosis Transmembrane Conductance Regulator/chemistry; Cystic Fibrosis Transmembrane Conductance Regulator/genetics; Diarrhea/drug therapy; Diarrhea/genetics; Diarrhea/metabolism; Drug Discovery; Epithelial Cells/metabolism; Humans; Molecular Targeted Therapy; Multiprotein Complexes/antagonists & inhibitors; Phosphoproteins/chemistry; Phosphoproteins/genetics; Protein Binding; Protein Interaction Domains and Motifs; Receptors, Lysophosphatidic Acid/chemistry; Receptors, Lysophosphatidic Acid/genetics; Signal Transduction/drug effects; Sodium-Hydrogen Exchangers/chemistry; Sodium-Hydrogen Exchangers/genetics

Key words

ABC transporters; CFTR; LPA2; NHERF2; cystic fibrosis; macromolecular protein complex; secretory diarrhea

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phosphoproteins / Sodium-Hydrogen Exchangers / Cystic Fibrosis Transmembrane Conductance Regulator / Respiratory Mucosa / Multiprotein Complexes / Receptors, Lysophosphatidic Acid / Intestinal Mucosa Limits: Animals / Humans Language: En Journal: Int J Mol Sci Year: 2017 Document type: Article Affiliation country: United States Country of publication: Switzerland

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