Identification of extant vertebrate <i>Myxine glutinosa</i> VWF: evolutionary conservation of primary hemostasis.

Grant, Marianne A; Beeler, David L; Spokes, Katherine C; Chen, Junmei; Dharaneeswaran, Harita; Sciuto, Tracey E; Dvorak, Ann M; Interlandi, Gianluca; Lopez, José A; Aird, William C

Identification of extant vertebrate Myxine glutinosa VWF: evolutionary conservation of primary hemostasis.

Grant, Marianne A; Beeler, David L; Spokes, Katherine C; Chen, Junmei; Dharaneeswaran, Harita; Sciuto, Tracey E; Dvorak, Ann M; Interlandi, Gianluca; Lopez, José A; Aird, William C.

Affiliation

Grant MA; Center for Vascular Biology Research, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA.
Beeler DL; Mount Desert Island Biological Laboratory, Salisbury Cove, ME.
Spokes KC; Center for Vascular Biology Research, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA.
Chen J; Center for Vascular Biology Research, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA.
Dharaneeswaran H; Bloodworks Research Institute, University of Washington, Seattle, WA.
Sciuto TE; Center for Vascular Biology Research, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA.
Dvorak AM; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA; and.
Interlandi G; Department of Pathology, Beth Israel Deaconess Medical Center, Boston, MA; and.
Lopez JA; Department of Bioengineering, University of Washington, Seattle, WA.
Aird WC; Bloodworks Research Institute, University of Washington, Seattle, WA.

Blood ; 130(23): 2548-2558, 2017 12 07.

Article in En | MEDLINE | ID: mdl-28899852

Subject(s)

Hagfishes; von Willebrand Factor/genetics; von Willebrand Factor/metabolism; ADAMTS13 Protein/metabolism; Amino Acid Sequence; Animals; CHO Cells; Cloning, Molecular; Cricetulus; DNA, Complementary; Endothelium, Vascular/metabolism; Evolution, Molecular; Gene Expression; Homeostasis; Humans; Models, Molecular; Platelet Aggregation; Protein Conformation; Protein Domains; Protein Folding; Protein Multimerization; Protein Processing, Post-Translational; Protein Transport; Proteolysis; Structure-Activity Relationship; Vertebrates; Weibel-Palade Bodies/metabolism; Weibel-Palade Bodies/ultrastructure; von Willebrand Factor/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Von Willebrand Factor / Hagfishes Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Humans Language: En Journal: Blood Year: 2017 Document type: Article Affiliation country: Morocco

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