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Downregulated SOCS1 expression activates the JAK1/STAT1 pathway and promotes polarization of macrophages into M1 type.
Liang, Yan-Bing; Tang, Hao; Chen, Zhi-Bin; Zeng, Li-Jin; Wu, Jing-Guo; Yang, Wen; Li, Zhen-Yu; Ma, Zhong-Fu.
Affiliation
  • Liang YB; Department of General Internal Medicine, The First Affiliated Hospital, Sun Yat­sen University, Guangzhou, Guangdong 510080, P.R. China.
  • Tang H; Department of General Internal Medicine, The First Affiliated Hospital, Sun Yat­sen University, Guangzhou, Guangdong 510080, P.R. China.
  • Chen ZB; Department of General Internal Medicine, The First Affiliated Hospital, Sun Yat­sen University, Guangzhou, Guangdong 510080, P.R. China.
  • Zeng LJ; Department of General Internal Medicine, The First Affiliated Hospital, Sun Yat­sen University, Guangzhou, Guangdong 510080, P.R. China.
  • Wu JG; Department of General Internal Medicine, The First Affiliated Hospital, Sun Yat­sen University, Guangzhou, Guangdong 510080, P.R. China.
  • Yang W; Department of General Internal Medicine, The First Affiliated Hospital, Sun Yat­sen University, Guangzhou, Guangdong 510080, P.R. China.
  • Li ZY; Department of General Internal Medicine, The First Affiliated Hospital, Sun Yat­sen University, Guangzhou, Guangdong 510080, P.R. China.
  • Ma ZF; Department of General Internal Medicine, The First Affiliated Hospital, Sun Yat­sen University, Guangzhou, Guangdong 510080, P.R. China.
Mol Med Rep ; 16(5): 6405-6411, 2017 Nov.
Article in En | MEDLINE | ID: mdl-28901399
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Macrophages, Peritoneal / STAT1 Transcription Factor / Janus Kinase 1 / Suppressor of Cytokine Signaling 1 Protein Limits: Animals Language: En Journal: Mol Med Rep Year: 2017 Document type: Article Country of publication: Greece
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Macrophages, Peritoneal / STAT1 Transcription Factor / Janus Kinase 1 / Suppressor of Cytokine Signaling 1 Protein Limits: Animals Language: En Journal: Mol Med Rep Year: 2017 Document type: Article Country of publication: Greece