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Recombinant ADAMTS-13: first-in-human pharmacokinetics and safety in congenital thrombotic thrombocytopenic purpura.
Scully, Marie; Knöbl, Paul; Kentouche, Karim; Rice, Lawrence; Windyga, Jerzy; Schneppenheim, Reinhard; Kremer Hovinga, Johanna A; Kajiwara, Michiko; Fujimura, Yoshihiro; Maggiore, Caterina; Doralt, Jennifer; Hibbard, Christopher; Martell, Leah; Ewenstein, Bruce.
Affiliation
  • Scully M; Department of Haematology and Cardiometabolic BRC, University College London Hospitals/University College London, London, United Kingdom.
  • Knöbl P; Division of Hematology and Hemostasis, Department of Medicine 1, Medical University of Vienna, Austria.
  • Kentouche K; Jena University Hospital, Jena, Germany.
  • Rice L; Department of Medicine, Houston Methodist Hospital, Weill Cornell Medical College, Houston, TX.
  • Windyga J; Department Disorders of Hemostasis and Internal Medicine, Institute of Hematology and Transfusion Medicine, Warsaw, Poland.
  • Schneppenheim R; Department of Pediatric Hematology and Oncology, Universitaetsklinikum Hamburg-Eppendorf, Hamburg, Germany.
  • Kremer Hovinga JA; Inselspital, University Hospital Bern, Bern, Switzerland.
  • Kajiwara M; Tokyo Medical and Dental University Hospital Faculty of Medicine, Tokyo, Japan.
  • Fujimura Y; Nara Medical University, Nara, Japan.
  • Maggiore C; Quintiles, Milan, Italy.
  • Doralt J; Shire, Vienna, Austria; and.
  • Hibbard C; Shire, Cambridge, MA.
  • Martell L; Shire, Cambridge, MA.
  • Ewenstein B; Shire, Cambridge, MA.
Blood ; 130(19): 2055-2063, 2017 11 09.
Article in En | MEDLINE | ID: mdl-28912376
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Purpura, Thrombotic Thrombocytopenic / ADAMTS13 Protein Type of study: Clinical_trials Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: Blood Year: 2017 Document type: Article Affiliation country: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Purpura, Thrombotic Thrombocytopenic / ADAMTS13 Protein Type of study: Clinical_trials Limits: Adolescent / Adult / Female / Humans / Male Language: En Journal: Blood Year: 2017 Document type: Article Affiliation country: United kingdom