Measurement of micronuclei and internal dose in mice demonstrates that 3-monochloropropane-1,2-diol (3-MCPD) has no genotoxic potency in vivo.

Aasa, Jenny; Törnqvist, Margareta; Abramsson-Zetterberg, Lilianne

Measurement of micronuclei and internal dose in mice demonstrates that 3-monochloropropane-1,2-diol (3-MCPD) has no genotoxic potency in vivo.

Aasa, Jenny; Törnqvist, Margareta; Abramsson-Zetterberg, Lilianne.

Affiliation

Aasa J; Department of Environmental Science and Analytical Chemistry, Stockholm University, Sweden.
Törnqvist M; Department of Environmental Science and Analytical Chemistry, Stockholm University, Sweden. Electronic address: margareta.tornqvist@aces.su.se.
Abramsson-Zetterberg L; Department of Environmental Science and Analytical Chemistry, Stockholm University, Sweden; National Food Agency, Uppsala, Sweden. Electronic address: lilianne.abramsson@slv.se.

Food Chem Toxicol ; 109(Pt 1): 414-420, 2017 Nov.

Article in En | MEDLINE | ID: mdl-28917435

Subject(s)

DNA Damage/drug effects; Micronucleus, Germline/drug effects; alpha-Chlorohydrin/toxicity; Animals; Erythrocytes/drug effects; Female; Mice; Mice, Inbred BALB C; Micronucleus, Germline/genetics; alpha-Chlorohydrin/administration & dosage

Key words

3-MCPD; Genotoxicity; Hb adducts; In vivo; Mice; Micronucleated erythrocytes in peripheral blood

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Micronucleus, Germline / Alpha-Chlorohydrin Limits: Animals Language: En Journal: Food Chem Toxicol Year: 2017 Document type: Article Affiliation country: Sweden Country of publication: United kingdom

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