RESOLUTION OF TREATMENT-RESISTANT SUBRETINAL FLUID IN A PATIENT WITH EXUDATIVE AGE-RELATED MACULAR DEGENERATION FOLLOWING ENDOPHTHALMITIS.
Retin Cases Brief Rep
; 11(4): 316-318, 2017.
Article
in En
| MEDLINE
| ID: mdl-28925926
ABSTRACT
PURPOSE:
This is the first report to the best of the authors' knowledge to show resolution of subretinal fluid and treatment requirement in a case of exudative age-related macular degeneration (eAMD) with persistent fluid despite treatment that resolved following an episode of culture-positive bacterial endophthalmitis.METHODS:
A 73-year-old man with history of eAMD of the right eye presented with acute postinjection bacterial endophthalmitis 3 days after injection. He had a history of only partially treatment-responsive eAMD that had been treated over a period of 8 years.RESULTS:
After tap-and-inject treatment of endophthalmitis with ceftazidime, vancomycin, and dexamethasone, the patient returned for follow-up with visual improvement and resolution of the subretinal fluid. The previously treatment-resistant eAMD remains quiescent without further treatment after 10 months of follow-up.CONCLUSION:
It is possible that some aspect of the infection, inflammation, or treatment of endophthalmitis had a disease-modifying impact on the eAMD. Further research into the components of endophthalmitis and its treatment may result in the discovery of new treatment approaches or treatment targets.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Eye Infections, Bacterial
/
Endophthalmitis
/
Wet Macular Degeneration
/
Subretinal Fluid
/
Anti-Inflammatory Agents
/
Anti-Bacterial Agents
Limits:
Aged
/
Humans
/
Male
Language:
En
Journal:
Retin Cases Brief Rep
Year:
2017
Document type:
Article