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Acrolein Disrupts Tight Junction Proteins and Causes Endoplasmic Reticulum Stress-Mediated Epithelial Cell Death Leading to Intestinal Barrier Dysfunction and Permeability.
Chen, Wei-Yang; Wang, Min; Zhang, Jingwen; Barve, Shirish S; McClain, Craig J; Joshi-Barve, Swati.
Affiliation
  • Chen WY; Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky; Alcohol Research Center, University of Louisville, Louisville, Kentucky.
  • Wang M; Alcohol Research Center, University of Louisville, Louisville, Kentucky; Department of Medicine, University of Louisville, Louisville, Kentucky; Hepatobiology and Toxicology Center, University of Louisville, Louisville, Kentucky.
  • Zhang J; Alcohol Research Center, University of Louisville, Louisville, Kentucky; Department of Medicine, University of Louisville, Louisville, Kentucky; Hepatobiology and Toxicology Center, University of Louisville, Louisville, Kentucky.
  • Barve SS; Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky; Alcohol Research Center, University of Louisville, Louisville, Kentucky; Department of Medicine, University of Louisville, Louisville, Kentucky; Hepatobiology and Toxicology Center, University of Louisville, L
  • McClain CJ; Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky; Alcohol Research Center, University of Louisville, Louisville, Kentucky; Department of Medicine, University of Louisville, Louisville, Kentucky; Hepatobiology and Toxicology Center, University of Louisville, L
  • Joshi-Barve S; Department of Pharmacology and Toxicology, University of Louisville, Louisville, Kentucky; Alcohol Research Center, University of Louisville, Louisville, Kentucky; Department of Medicine, University of Louisville, Louisville, Kentucky; Hepatobiology and Toxicology Center, University of Louisville, L
Am J Pathol ; 187(12): 2686-2697, 2017 Dec.
Article in En | MEDLINE | ID: mdl-28935573
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acrolein / Apoptosis / Endoplasmic Reticulum Stress / Tight Junction Proteins / Intestinal Mucosa Type of study: Etiology_studies Limits: Animals / Humans / Male Language: En Journal: Am J Pathol Year: 2017 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Acrolein / Apoptosis / Endoplasmic Reticulum Stress / Tight Junction Proteins / Intestinal Mucosa Type of study: Etiology_studies Limits: Animals / Humans / Male Language: En Journal: Am J Pathol Year: 2017 Document type: Article Country of publication: United States