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The Cks1/Cks2 axis fine-tunes Mll1 expression and is crucial for MLL-rearranged leukaemia cell viability.
Grey, William; Ivey, Adam; Milne, Thomas A; Haferlach, Torsten; Grimwade, David; Uhlmann, Frank; Voisset, Edwige; Yu, Veronica.
Affiliation
  • Grey W; Department of Medical and Molecular Genetics, King's College London, Faculty of Life Sciences and Medicine, London, UK. Electronic address: william.grey@crick.ac.uk.
  • Ivey A; Department of Medical and Molecular Genetics, King's College London, Faculty of Life Sciences and Medicine, London, UK.
  • Milne TA; MRC Molecular Haematology Unit, Weatherall Institute of Molecular Medicine, NIHR Oxford Biomedical Research Centre Programme, University of Oxford, UK.
  • Haferlach T; MLL Munich Leukemia Laboratory, Munich, Germany.
  • Grimwade D; Department of Medical and Molecular Genetics, King's College London, Faculty of Life Sciences and Medicine, London, UK.
  • Uhlmann F; Chromosome Segregation Laboratory, The Francis Crick Institute, London, UK.
  • Voisset E; Department of Medical and Molecular Genetics, King's College London, Faculty of Life Sciences and Medicine, London, UK. Electronic address: edwige.voisset@kcl.ac.uk.
  • Yu V; Department of Medical and Molecular Genetics, King's College London, Faculty of Life Sciences and Medicine, London, UK.
Biochim Biophys Acta Mol Cell Res ; 1865(1): 105-116, 2018 Jan.
Article in En | MEDLINE | ID: mdl-28939057

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia / Carrier Proteins / Histone-Lysine N-Methyltransferase / Cell Cycle Proteins / CDC2-CDC28 Kinases / Myeloid-Lymphoid Leukemia Protein Limits: Animals / Humans Language: En Journal: Biochim Biophys Acta Mol Cell Res Year: 2018 Document type: Article Country of publication: Netherlands

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Leukemia / Carrier Proteins / Histone-Lysine N-Methyltransferase / Cell Cycle Proteins / CDC2-CDC28 Kinases / Myeloid-Lymphoid Leukemia Protein Limits: Animals / Humans Language: En Journal: Biochim Biophys Acta Mol Cell Res Year: 2018 Document type: Article Country of publication: Netherlands