Your browser doesn't support javascript.
loading
Fluorescence Microscopy of Nanochannel-Confined DNA.
Westerlund, Fredrik; Persson, Fredrik; Fritzsche, Joachim; Beech, Jason P; Tegenfeldt, Jonas O.
Affiliation
  • Westerlund F; Chalmers University of Technology, Gothenburg, Sweden.
  • Persson F; Vanadis Diagnostics, Sollentuna, Sweden.
  • Fritzsche J; Chalmers University of Technology, Gothenburg, Sweden.
  • Beech JP; NanoLund and Department of Physics, Lund University, PO Box 118, 22100, Lund, Sweden.
  • Tegenfeldt JO; NanoLund and Department of Physics, Lund University, PO Box 118, 22100, Lund, Sweden. Jonas.tegenfeldt@ftf.lth.se.
Methods Mol Biol ; 1665: 173-198, 2018.
Article in En | MEDLINE | ID: mdl-28940070
Stretching of DNA in nanoscale confinement allows for several important studies. The genetic contents of the DNA can be visualized on the single DNA molecule level and both the polymer physics of confined DNA and also DNA/protein and other DNA/DNA-binding molecule interactions can be explored. This chapter describes the basic steps to fabricate the nanostructures, perform the experiments and analyze the data.
Subject(s)
Key words

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Nanotechnology / Nanostructures / Microscopy, Fluorescence Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2018 Document type: Article Affiliation country: Sweden Country of publication: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA / Nanotechnology / Nanostructures / Microscopy, Fluorescence Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2018 Document type: Article Affiliation country: Sweden Country of publication: United States