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The caffeoyl phenylethanoid glycosides from Lindernia ruellioides and their anti-HBV effects.
Wei, Jing-Chen; Wang, Peng-Cheng; Zhou, Xian-Li; Tang, Kun; Luo, Qin; Xu, Qin; Chen, Xue-Jiao; Liang, Cheng-Qin; Chen, Xu.
Affiliation
  • Wei JC; a College of Pharmacy , Guilin Medical University , Guilin 541004 , China.
  • Wang PC; b Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair , Guilin Medical University , Guilin 541001 , China.
  • Zhou XL; a College of Pharmacy , Guilin Medical University , Guilin 541004 , China.
  • Tang K; a College of Pharmacy , Guilin Medical University , Guilin 541004 , China.
  • Luo Q; c Department of Pharmacy , Affiliated Hospital of Guilin Medical University , Guilin 541004 , China.
  • Xu Q; a College of Pharmacy , Guilin Medical University , Guilin 541004 , China.
  • Chen XJ; a College of Pharmacy , Guilin Medical University , Guilin 541004 , China.
  • Liang CQ; b Guangxi Key Laboratory of Molecular Medicine in Liver Injury and Repair , Guilin Medical University , Guilin 541001 , China.
  • Chen X; a College of Pharmacy , Guilin Medical University , Guilin 541004 , China.
J Asian Nat Prod Res ; 20(8): 757-762, 2018 Aug.
Article in En | MEDLINE | ID: mdl-28944682
ABSTRACT
Five caffeoyl phenylethanoid glycosides, including two new ones linderruelliosides A (1) and B (2), were isolated from the leaves and stems of Lindernia ruellioides. Their structures were elucidated on the basis of spectroscopic methods, including extensive NMR and MS spectra. In addition, all these compounds were tested for their anti-HBV activity. Compounds 1, 3, and 4 showed anti-HBV activities, with IC50 values of 54.87, 30.74, and 69.02 µM for HBsAg and 26.70, 5.17, and 7.08 µM for HBeAg, respectively.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Hepatitis B virus / Scrophulariaceae Limits: Humans Country/Region as subject: Asia Language: En Journal: J Asian Nat Prod Res Journal subject: BOTANICA / QUIMICA Year: 2018 Document type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Hepatitis B virus / Scrophulariaceae Limits: Humans Country/Region as subject: Asia Language: En Journal: J Asian Nat Prod Res Journal subject: BOTANICA / QUIMICA Year: 2018 Document type: Article Affiliation country: China