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BCL-xL-selective BH3 mimetic sensitizes rhabdomyosarcoma cells to chemotherapeutics by activation of the mitochondrial pathway of apoptosis.
Faqar-Uz-Zaman, Sara Fatima; Heinicke, Ulrike; Meister, Michael Torsten; Vogler, Meike; Fulda, Simone.
Affiliation
  • Faqar-Uz-Zaman SF; Institute for Experimental Cancer Research in Pediatrics, Goethe-University, Komturstrasse 3a, 60528 Frankfurt, Germany.
  • Heinicke U; Institute for Experimental Cancer Research in Pediatrics, Goethe-University, Komturstrasse 3a, 60528 Frankfurt, Germany.
  • Meister MT; Institute for Experimental Cancer Research in Pediatrics, Goethe-University, Komturstrasse 3a, 60528 Frankfurt, Germany; German Cancer Consortium (DKTK), Partner Site Frankfurt, Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Department of Pediatric Hematology and Onc
  • Vogler M; Institute for Experimental Cancer Research in Pediatrics, Goethe-University, Komturstrasse 3a, 60528 Frankfurt, Germany.
  • Fulda S; Institute for Experimental Cancer Research in Pediatrics, Goethe-University, Komturstrasse 3a, 60528 Frankfurt, Germany; German Cancer Consortium (DKTK), Partner Site Frankfurt, Heidelberg, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany. Electronic address: simone.fulda@kgu.de.
Cancer Lett ; 412: 131-142, 2018 01 01.
Article in En | MEDLINE | ID: mdl-28947136

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rhabdomyosarcoma / Apoptosis / Bcl-X Protein / Mitochondria / Antineoplastic Agents Limits: Humans Language: En Journal: Cancer Lett Year: 2018 Document type: Article Affiliation country: Germany Country of publication: Ireland

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Rhabdomyosarcoma / Apoptosis / Bcl-X Protein / Mitochondria / Antineoplastic Agents Limits: Humans Language: En Journal: Cancer Lett Year: 2018 Document type: Article Affiliation country: Germany Country of publication: Ireland