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Phase 1 trials of PEGylated recombinant human hyaluronidase PH20 in patients with advanced solid tumours.
Infante, Jeffrey R; Korn, Ronald L; Rosen, Lee S; LoRusso, Patricia; Dychter, Samuel S; Zhu, Joy; Maneval, Daniel C; Jiang, Ping; Shepard, H Michael; Frost, Gregory; Von Hoff, Daniel D; Borad, Mitesh J; Ramanathan, Ramesh K.
Affiliation
  • Infante JR; Early Development Oncology, Janssen Research & Development, LLC, Welsh & McKean Roads, Spring House, PA 19477, USA.
  • Korn RL; Scottsdale Medical Imaging, 9700 N. 91st Suite C-200, Scottsdale, AZ 85258, USA.
  • Rosen LS; Division of Hematology-Oncology, University of California - Los Angeles, 2020 Santa Monica Boulevard, Suite 600, Santa Monica, CA 90404, USA.
  • LoRusso P; Yale Cancer Center, PO Box 208028, New Haven, CT 06520, USA.
  • Dychter SS; Fate Therapeutics, Inc., 3535 General Atomics Court, San Diego, CA 92121, USA.
  • Zhu J; SBIO Pte, Ltd., 1 Science Park Road, #05-09, The Capricorn Science Park 2, Singapore, 117 528, Singapore.
  • Maneval DC; Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, CA 92121, USA.
  • Jiang P; Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, CA 92121, USA.
  • Shepard HM; Halozyme Therapeutics, Inc., 11388 Sorrento Valley Road, San Diego, CA 92121, USA.
  • Frost G; F1 Bioventures LLC, 505 S. Flagler Drive, West Palm Beach, FL 33401, USA.
  • Von Hoff DD; Translational Genomics Research Institute (TGen), 445 N. Fifth Street, Phoenix, AZ 85004, USA.
  • Borad MJ; Mayo Clinic, 13400 E. Shea Boulevard, Scottsdale, AZ 85259, USA.
  • Ramanathan RK; Mayo Clinic, 13400 E. Shea Boulevard, Scottsdale, AZ 85259, USA.
Br J Cancer ; 118(2): 153-161, 2018 01.
Article in En | MEDLINE | ID: mdl-28949957

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Hyaluronoglucosaminidase / Neoplasms Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Br J Cancer Year: 2018 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Polyethylene Glycols / Hyaluronoglucosaminidase / Neoplasms Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Br J Cancer Year: 2018 Document type: Article Affiliation country: United States