Control of HIV-1 by an HLA-B*52:01-C*12:02 Protective Haplotype.

Chikata, Takayuki; Murakoshi, Hayato; Koyanagi, Madoka; Honda, Kazutaka; Gatanaga, Hiroyuki; Oka, Shinichi; Takiguchi, Masafumi

Chikata, Takayuki; Murakoshi, Hayato; Koyanagi, Madoka; Honda, Kazutaka; Gatanaga, Hiroyuki; Oka, Shinichi; Takiguchi, Masafumi.

Affiliation

Chikata T; Center for AIDS Research, Kumamoto University, Tokyo, Japan.
Murakoshi H; Center for AIDS Research, Kumamoto University, Tokyo, Japan.
Koyanagi M; Center for AIDS Research, Kumamoto University, Tokyo, Japan.
Honda K; Center for AIDS Research, Kumamoto University, Tokyo, Japan.
Gatanaga H; Center for AIDS Research, Kumamoto University, Tokyo, Japan.
Oka S; AIDS Clinical Center, National Center for Global Health and Medicine, Tokyo, Japan.
Takiguchi M; Center for AIDS Research, Kumamoto University, Tokyo, Japan.

J Infect Dis ; 216(11): 1415-1424, 2017 12 12.

Article in En | MEDLINE | ID: mdl-28968792

Subject(s)

HIV-1/drug effects; HLA-B Antigens/pharmacology; HLA-B52 Antigen/pharmacology; HLA-C Antigens/pharmacology; Haplotypes/immunology; Alleles; Cell Line; Chromium/analysis; Cytokines/analysis; Epitopes, T-Lymphocyte; HIV Infections/diet therapy; HIV Infections/immunology; HIV Infections/virology; HLA-B Antigens/immunology; HLA-B52 Antigen/immunology; HLA-C Antigens/immunology; HLA-C Antigens/isolation & purification; Host-Pathogen Interactions; Humans; Immunodominant Epitopes/pharmacology; Killer Cells, Natural/drug effects; Killer Cells, Natural/immunology; Receptors, KIR2DL2/physiology; T-Lymphocytes, Cytotoxic/drug effects; T-Lymphocytes, Cytotoxic/immunology; Virus Replication/drug effects; nef Gene Products, Human Immunodeficiency Virus/immunology; nef Gene Products, Human Immunodeficiency Virus/pharmacology; pol Gene Products, Human Immunodeficiency Virus/immunology; pol Gene Products, Human Immunodeficiency Virus/pharmacology

Key words

CTL; HIV-1; HLA-B*52:01; HLA-C*12:02; haplotype

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Haplotypes / HLA-B Antigens / HLA-C Antigens / HIV-1 / HLA-B52 Antigen Limits: Humans Language: En Journal: J Infect Dis Year: 2017 Document type: Article Affiliation country: Japan Country of publication: United States

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