Capturing Three-Dimensional Genome Organization in Individual Cells by Single-Cell Hi-C.

Nagano, Takashi; Wingett, Steven W; Fraser, Peter

Nagano, Takashi; Wingett, Steven W; Fraser, Peter.

Affiliation

Nagano T; Nuclear Dynamics Programme, The Babraham Institute, Cambridge, UK. takashi.nagano@babraham.ac.uk.
Wingett SW; Nuclear Dynamics Programme, The Babraham Institute, Cambridge, UK.
Fraser P; Nuclear Dynamics Programme, The Babraham Institute, Cambridge, UK.

Methods Mol Biol ; 1654: 79-97, 2017.

Article in En | MEDLINE | ID: mdl-28986784

Subject(s)

Chromosomes/genetics; Single-Cell Analysis/methods; Animals; Cell Nucleus/genetics; Gene Library; Humans; Nucleic Acid Conformation

Key words

Chromatin interactions; Chromosome conformation capture (3C); Genome organization; Hi-C; In-nucleus ligation; In-solution ligation; Single-cell analysis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Chromosomes / Single-Cell Analysis Limits: Animals / Humans Language: En Journal: Methods Mol Biol Journal subject: BIOLOGIA MOLECULAR Year: 2017 Document type: Article Affiliation country: United kingdom

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