Bone Marrow Findings Secondary to Antineoplastic Compounds: Hematopoietic, Bone, and Cytokine Cross Talk.

Loberg, Lise I; Logan, Michael; Barnhart, Kirstin; Fossey, Stacey; Whitney, Katharine

Loberg, Lise I; Logan, Michael; Barnhart, Kirstin; Fossey, Stacey; Whitney, Katharine.

Affiliation

Loberg LI; 1 Preclinical Safety, AbbVie, Inc., North Chicago, Illinois, USA.
Logan M; 1 Preclinical Safety, AbbVie, Inc., North Chicago, Illinois, USA.
Barnhart K; 1 Preclinical Safety, AbbVie, Inc., North Chicago, Illinois, USA.
Fossey S; 2 Preclinical Safety, AbbVie, Inc., Worcester, Massachusetts, USA.
Whitney K; 1 Preclinical Safety, AbbVie, Inc., North Chicago, Illinois, USA.

Toxicol Pathol ; 45(7): 879-883, 2017 10.

Article in En | MEDLINE | ID: mdl-28990496

Subject(s)

Antineoplastic Agents/adverse effects; Bone Marrow/drug effects; Cytokines/metabolism; Hematopoietic System/drug effects; Animals; Antineoplastic Agents/administration & dosage; Bone Marrow/metabolism; Dose-Response Relationship, Drug; Female; Granulocyte Colony-Stimulating Factor/administration & dosage; Granulocyte Colony-Stimulating Factor/adverse effects; Hematopoietic System/metabolism; Hemoglobins/metabolism; Humans; Male; Mice; Models, Animal; Neutrophils/metabolism; Rats

Key words

bone; bone marrow; cytokine; growth factors; hematopoietic system; secondary effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Marrow / Cytokines / Hematopoietic System / Antineoplastic Agents Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Toxicol Pathol Year: 2017 Document type: Article Affiliation country: United States

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