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A convenient UHPLC-MS/MS method for routine monitoring of plasma and brain levels of nicotine and cotinine as a tool to validate newly developed preclinical smoking model in mouse.
Kaisar, Mohammad A; Kallem, Raja Reddy; Sajja, Ravi K; Sifat, Ali Ehsan; Cucullo, Luca.
Affiliation
  • Kaisar MA; Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, 1300 S. Coulter Street, Amarillo, TX, 79106, USA.
  • Kallem RR; Office of Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, Amarillo, TX, 79106, USA.
  • Sajja RK; Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, 1300 S. Coulter Street, Amarillo, TX, 79106, USA.
  • Sifat AE; Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, 1300 S. Coulter Street, Amarillo, TX, 79106, USA.
  • Cucullo L; Department of Pharmaceutical Sciences, School of Pharmacy, Texas Tech University Health Sciences Center, 1300 S. Coulter Street, Amarillo, TX, 79106, USA. luca.cucullo@ttuhsc.edu.
BMC Neurosci ; 18(1): 71, 2017 10 11.
Article in En | MEDLINE | ID: mdl-29020944

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Smoking / Cotinine / Tandem Mass Spectrometry / Nicotine Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: BMC Neurosci Journal subject: NEUROLOGIA Year: 2017 Document type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Smoking / Cotinine / Tandem Mass Spectrometry / Nicotine Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: BMC Neurosci Journal subject: NEUROLOGIA Year: 2017 Document type: Article Affiliation country: United States