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In vivo pharmacokinetic interaction by ethanolic extract of Gymnema sylvestre with CYP2C9 (Tolbutamide), CYP3A4 (Amlodipine) and CYP1A2 (Phenacetin) in rats.
Vaghela, Madhuri; Sahu, Niteshkumar; Kharkar, Prashant; Pandita, Nancy.
Affiliation
  • Vaghela M; Department of Chemistry, Sunandan Divatia School of Science, SVKM's NMIMS University, Mumbai 400056, Maharashtra, India. Electronic address: madhuri.vaghela@nmims.edu.in.
  • Sahu N; Department of Pharmaceutical Chemistry, SPP-School of Pharmacy and Technology Management, SVKM's NMIMS University, Mumbai 400056, Maharashtra, India.
  • Kharkar P; Department of Pharmaceutical Chemistry, SPP-School of Pharmacy and Technology Management, SVKM's NMIMS University, Mumbai 400056, Maharashtra, India.
  • Pandita N; Department of Chemistry, Sunandan Divatia School of Science, SVKM's NMIMS University, Mumbai 400056, Maharashtra, India. Electronic address: nancy.pandita@nmims.edu.
Chem Biol Interact ; 278: 141-151, 2017 Dec 25.
Article in En | MEDLINE | ID: mdl-29042257

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tolbutamide / Plant Extracts / Phenacetin / Amlodipine / Cytochrome P-450 CYP1A2 / Gymnema sylvestre / Cytochrome P-450 CYP3A / Cytochrome P-450 CYP2C9 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Chem Biol Interact Year: 2017 Document type: Article Country of publication: Ireland

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tolbutamide / Plant Extracts / Phenacetin / Amlodipine / Cytochrome P-450 CYP1A2 / Gymnema sylvestre / Cytochrome P-450 CYP3A / Cytochrome P-450 CYP2C9 Type of study: Prognostic_studies Limits: Animals Language: En Journal: Chem Biol Interact Year: 2017 Document type: Article Country of publication: Ireland