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HIV-1 viral protein R (Vpr) induces fatty liver in mice via LXRα and PPARα dysregulation: implications for HIV-specific pathogenesis of NAFLD.
Agarwal, Neeti; Iyer, Dinakar; Gabbi, Chiara; Saha, Pradip; Patel, Sanjeet G; Mo, Qianxing; Chang, Benny; Goswami, Biman; Schubert, Ulrich; Kopp, Jeffrey B; Lewis, Dorothy E; Balasubramanyam, Ashok.
Affiliation
  • Agarwal N; Translational Metabolism Unit, Diabetes Research Center, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Iyer D; Translational Metabolism Unit, Diabetes Research Center, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Gabbi C; Department of Molecular Biology, University of Houston, Houston, TX, USA.
  • Saha P; University of Houston, Department of Biology and Biochemistry, Houston, TX, USA.
  • Patel SG; Translational Metabolism Unit, Diabetes Research Center, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Mo Q; Department of Surgery, UCLA, Los Angeles, CA, USA.
  • Chang B; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA.
  • Goswami B; Translational Metabolism Unit, Diabetes Research Center, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Schubert U; Translational Metabolism Unit, Diabetes Research Center, Division of Diabetes, Endocrinology and Metabolism, Department of Medicine, Baylor College of Medicine, Houston, TX, USA.
  • Kopp JB; Institute of Virology, Friedrich-Alexander University Erlangen-Nürnberg (FAU), Erlangen, Germany.
  • Lewis DE; Kidney Disease Section, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Balasubramanyam A; Division of Infectious Diseases, Department of Medicine, University of Texas Health Sciences Center, Houston, TX, USA.
Sci Rep ; 7(1): 13362, 2017 10 17.
Article in En | MEDLINE | ID: mdl-29042644
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / Gene Products, vpr / PPAR alpha / Non-alcoholic Fatty Liver Disease / Liver X Receptors Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV Infections / HIV-1 / Gene Products, vpr / PPAR alpha / Non-alcoholic Fatty Liver Disease / Liver X Receptors Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies Limits: Animals Language: En Journal: Sci Rep Year: 2017 Document type: Article Affiliation country: United States Country of publication: United kingdom