Your browser doesn't support javascript.
loading
A survey-based study identifies common but unrecognized symptoms in a large series of juvenile Huntington's disease.
Moser, Amelia D; Epping, Eric; Espe-Pfeifer, Patricia; Martin, Erin; Zhorne, Leah; Mathews, Katherine; Nance, Martha; Hudgell, Denise; Quarrell, Oliver; Nopoulos, Peg.
Affiliation
  • Moser AD; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
  • Epping E; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
  • Espe-Pfeifer P; Departments of Psychiatry & Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
  • Martin E; Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
  • Zhorne L; Departments of Pediatrics & Neurology, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
  • Mathews K; Departments of Pediatrics & Neurology, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
  • Nance M; Struthers Parkinson's Center, Minneapolis, MN, USA.
  • Hudgell D; Help4HD International, Santa Maria, CA, USA.
  • Quarrell O; Department of Clinical Genetics, Sheffield Children's Hospital, Sheffield, UK.
  • Nopoulos P; Departments of Psychiatry, Pediatrics, & Neurology, University of Iowa Carver College of Medicine, Iowa City, IA, USA.
Neurodegener Dis Manag ; 7(5): 307-315, 2017 Oct.
Article in En | MEDLINE | ID: mdl-29043929
ABSTRACT

AIM:

The symptoms of Huntington's disease are well known, yet the symptoms of juvenile Huntington's disease (JHD) are less established due to its rarity. The study examined a cluster of symptoms considered to be common, but under-recognized in JHD pain, itching, sleeping difficulties, psychosis and tics. MATERIALS &

METHODS:

A symptom survey was constructed using the online tool Qualtrics and dispersed to JHD caregivers through websites.

RESULTS:

A total of 33 surveys were completed. Disrupted sleep was the most prevalent symptom (87%), followed by tics (78%), pain (69%), itching (60%) and psychosis (39%).

CONCLUSION:

Despite limitations, the study supports that there are symptoms in the JHD population that are not considered classic, however, are common and significant for patients and caregivers.
Subject(s)
Key words
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Huntington Disease Type of study: Diagnostic_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Language: En Journal: Neurodegener Dis Manag Year: 2017 Document type: Article Affiliation country: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Huntington Disease Type of study: Diagnostic_studies Limits: Adolescent / Adult / Child / Child, preschool / Female / Humans / Male Language: En Journal: Neurodegener Dis Manag Year: 2017 Document type: Article Affiliation country: United States