Diagnostic performance of a low dose triple rule-out CT angiography using SAFIRE in emergency department.
Diagn Interv Imaging
; 98(12): 881-891, 2017 Dec.
Article
in En
| MEDLINE
| ID: mdl-29066126
ABSTRACT
OBJECTIVES:
To compare the diagnostic performance of "triple rule out" CT angiography (TRO-CTA) at 100kVp using sinogram affirmed iterative reconstruction (SAFIRE) with TRO-CTA at 120kVp using filtered back projection (FBP) in patients with acute chest pain.METHODS:
Consecutive non-prepared patients from a single radiological emergency department, referred for acute chest pain evaluation with TRO-CTA, were randomly assigned to two different TRO-CTA protocols. Fifty patients (66% men; mean age, 66.6±19.0 [SD] years [range 24-97years]) had TRO-CTA at 120kVp with FBP and 97 patients (67% men; mean age, 62.8±17.9 [SD] years [range 24-93years]) had TRO-CTA at 100kVp with SAFIRE. Two radiologists reviewed the TRO-CTA images for pathologic findings and degree of diagnostic confidence. Image noise, vessel attenuation value, signal-to-noise and contrast-to-noise ratios in five main thoracic arteries were measured for objective and subjective analysis.RESULTS:
A total of 147 patients (98 men, 49 women; mean age, 64.7±18.4 [SD] [range, 24-97years) were included with good diagnostic confidence and equivalent pathological findings between the two TRO-CTA protocols. Objective and subjective analysis were identical between protocols and radiologists, except for vessel attenuation in the ascending aorta (P=0.02) and image noise in the pulmonary trunk (P=0.04). The effective radiation dose decreased significantly by 34% in the low dose TRO-CTA using SAFIRE protocol (5.7±2.7 vs 8.6±6.1mSv; P=4.7×10-6).CONCLUSIONS:
Low dose TRO-CTA protocol using SAFIRE allows a high confidence diagnostic level with the benefit of a 34% radiation dose decrease compared with a standard TRO-CTA protocol using FBP.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Computed Tomography Angiography
Type of study:
Clinical_trials
/
Diagnostic_studies
/
Guideline
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
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Male
/
Middle aged
Language:
En
Journal:
Diagn Interv Imaging
Year:
2017
Document type:
Article