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Inhibition of cholesterol biosynthesis through RNF145-dependent ubiquitination of SCAP.
Zhang, Li; Rajbhandari, Prashant; Priest, Christina; Sandhu, Jaspreet; Wu, Xiaohui; Temel, Ryan; Castrillo, Antonio; de Aguiar Vallim, Thomas Q; Sallam, Tamer; Tontonoz, Peter.
Affiliation
  • Zhang L; Department of Pathology and Laboratory Medicine, Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, United States.
  • Rajbhandari P; Department of Pathology and Laboratory Medicine, Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, United States.
  • Priest C; Department of Pathology and Laboratory Medicine, Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, United States.
  • Sandhu J; Department of Pathology and Laboratory Medicine, Howard Hughes Medical Institute, University of California, Los Angeles, Los Angeles, United States.
  • Wu X; Department of Medicine, Division of Cardiology, University of California, Los Angeles, Los Angeles, United States.
  • Temel R; Saha Cardiovascular Research Center, University of Kentucky, Lexington, United States.
  • Castrillo A; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, United States.
  • de Aguiar Vallim TQ; Instituto de Investigaciones Biomédicas Alberto Sols, CSIC-Universidad Autónoma de Madrid, Unidad de Biomedicina-Universidad de Las Palmas de Gran Canaria (Unidad asociada al CSIC), Las Palmas de Gran Canaria, Spain.
  • Sallam T; Instituto Universitario de Investigaciones Biomédicas y Sanitarias, Universidad de Las Palmas de Gran Canaria, Las Palmas de Gran Canaria, Spain.
  • Tontonoz P; Department of Medicine, Division of Cardiology, University of California, Los Angeles, Los Angeles, United States.
Elife ; 62017 10 25.
Article in En | MEDLINE | ID: mdl-29068315
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholesterol / Intracellular Signaling Peptides and Proteins / Membrane Proteins Limits: Animals Language: En Journal: Elife Year: 2017 Document type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholesterol / Intracellular Signaling Peptides and Proteins / Membrane Proteins Limits: Animals Language: En Journal: Elife Year: 2017 Document type: Article Affiliation country: United States