[Prognosis and treatment of glomerulonephritis of periarteritis nodosa. The role of plasma exchange]. / Pronostic et traitement des glomérulonéphrites de la périartérite noueuse. Place des échanges plasmatiques.
Ann Med Interne (Paris)
; 139 Suppl 1: 23-5, 1988.
Article
in Fr
| MEDLINE
| ID: mdl-2907849
ABSTRACT
Fourteen patients with polyarteritis nodosa complicated by histologically confirmed glomerulopathies were included in a prospective multi-center study comparing corticotherapy (group 1, n = 8) with combined cyclophosphamide and steroids (group 2, n = 6). Plasma exchanges were associated on a routine basis. The two groups were comparable apart from initially more severe renal impairment in group 1 (p less than 0.05). Initial control of the disease was obtained in 11 patients (7 from group 1, 4 from group 2) including the patients with oligoanuria. Six patients recovered, 3 had recurrence requiring chronic hemodialysis and 5 patients died from group 1 (p less than 0.05). These preliminary findings suggest that plasma exchange can contribute to control of polyarteritis nodosa with renal complications.
Search on Google
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Polyarteritis Nodosa
/
Plasma Exchange
/
Glomerulonephritis
Type of study:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limits:
Humans
Language:
Fr
Journal:
Ann Med Interne (Paris)
Year:
1988
Document type:
Article