Your browser doesn't support javascript.
loading
GA101 P329GLALA, a variant of obinutuzumab with abolished ADCC, ADCP and CDC function but retained cell death induction, is as efficient as rituximab in B-cell depletion and antitumor activity.
Herter, Sylvia; Herting, Frank; Muth, Gunter; van Puijenbroek, Erwin; Schlothauer, Tilman; Ferrara, Claudia; Brady, Kevin; Lang, Sabine; Bacac, Marina; Mössner, Ekkehard; Umana, Pablo; Klein, Christian.
Affiliation
  • Herter S; Roche Pharmaceutical Research & Early Development, 1Roche Innovation Center Zurich, Switzerland.
  • Herting F; Roche Innovation Center Munich, Germany.
  • Muth G; Roche Innovation Center Munich, Germany.
  • van Puijenbroek E; Roche Pharmaceutical Research & Early Development, 1Roche Innovation Center Zurich, Switzerland.
  • Schlothauer T; Roche Innovation Center Munich, Germany.
  • Ferrara C; Roche Pharmaceutical Research & Early Development, 1Roche Innovation Center Zurich, Switzerland.
  • Brady K; Roche Innovation Center Basel, Switzerland.
  • Lang S; Roche Pharmaceutical Research & Early Development, 1Roche Innovation Center Zurich, Switzerland.
  • Bacac M; Roche Pharmaceutical Research & Early Development, 1Roche Innovation Center Zurich, Switzerland.
  • Mössner E; Roche Pharmaceutical Research & Early Development, 1Roche Innovation Center Zurich, Switzerland.
  • Umana P; Roche Pharmaceutical Research & Early Development, 1Roche Innovation Center Zurich, Switzerland.
  • Klein C; Roche Pharmaceutical Research & Early Development, 1Roche Innovation Center Zurich, Switzerland christian.klein.ck1@roche.com.
Haematologica ; 103(2): e78-e81, 2018 02.
Article in En | MEDLINE | ID: mdl-29079598
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Cell Death / Antibodies, Monoclonal, Humanized / Rituximab / Antineoplastic Agents Limits: Humans Language: En Journal: Haematologica Year: 2018 Document type: Article Affiliation country: Switzerland Country of publication: Italy
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: B-Lymphocytes / Cell Death / Antibodies, Monoclonal, Humanized / Rituximab / Antineoplastic Agents Limits: Humans Language: En Journal: Haematologica Year: 2018 Document type: Article Affiliation country: Switzerland Country of publication: Italy