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B cell-derived IL-4 acts on podocytes to induce proteinuria and foot process effacement.
Kim, Alfred Hj; Chung, Jun-Jae; Akilesh, Shreeram; Koziell, Ania; Jain, Sanjay; Hodgin, Jeffrey B; Miller, Mark J; Stappenbeck, Thaddeus S; Miner, Jeffrey H; Shaw, Andrey S.
Affiliation
  • Kim AH; Division of Rheumatology, Department of Internal Medicine, and.
  • Chung JJ; Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Akilesh S; Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Koziell A; Department of Experimental Immunobiology, Division of Transplantation Immunology and Mucosal Biology, King's College London and Department of Paediatric Nephrology, Evelina Children's Hospital, London, United Kingdom.
  • Jain S; Renal Division, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Hodgin JB; Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA.
  • Miller MJ; Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Stappenbeck TS; Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Miner JH; Renal Division, Washington University School of Medicine, St. Louis, Missouri, USA.
  • Shaw AS; Division of Immunobiology, Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, Missouri, USA.
JCI Insight ; 2(21)2017 11 02.
Article in En | MEDLINE | ID: mdl-29093269
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteinuria / B-Lymphocytes / Interleukin-4 / Podocytes Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: JCI Insight Year: 2017 Document type: Article Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteinuria / B-Lymphocytes / Interleukin-4 / Podocytes Type of study: Prognostic_studies Limits: Animals / Female / Humans Language: En Journal: JCI Insight Year: 2017 Document type: Article Country of publication: United States