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Identification of single nucleotide polymorphisms of the PI3K-AKT-mTOR pathway as a risk factor of central nervous system metastasis in metastatic breast cancer.
Le Rhun, Emilie; Bertrand, Nicolas; Dumont, Aurélie; Tresch, Emmanuelle; Le Deley, Marie-Cécile; Mailliez, Audrey; Preusser, Matthias; Weller, Michael; Revillion, Françoise; Bonneterre, Jacques.
Affiliation
  • Le Rhun E; Univ. Lille, F-59000 Lille, France; Inserm, U-1192, F-59000 Lille, France; CHU Lille, General and Stereotaxic Neurosurgery service, F-59000 Lille, France; Oscar Lambret Center, Medical Oncology Department, F-59000 Lille, France. Electronic address: E-lerhun@o-lambret.fr.
  • Bertrand N; Univ. Lille, F-59000 Lille, France; Oscar Lambret Center, Medical Oncology Department, F-59000 Lille, France. Electronic address: nicolas.bertrand.onco@gmail.com.
  • Dumont A; Oscar Lambret Center, Human Molecular Oncology Unit, Lille, France; Clinical Division of Oncology, Department of Medicine 1, CNS Unit Comprehensive Cancer Center Vienna (CCC-CNS), Vienna, Austria. Electronic address: a-dumont@o-lambret.fr.
  • Tresch E; Oscar Lambret Center, Biostatistic Unit, Lille, France; Medical University of Vienna, Vienna, Austria. Electronic address: e-tresch@o-lambret.fr.
  • Le Deley MC; Univ. Lille, F-59000 Lille, France; Oscar Lambret Center, Biostatistic Unit, Lille, France; Medical University of Vienna, Vienna, Austria. Electronic address: m-ledeley@o-lambret.fr.
  • Mailliez A; Oscar Lambret Center, Medical Oncology Department, F-59000 Lille, France. Electronic address: a-mailliez@o-lambret.fr.
  • Preusser M; Oscar Lambret Center, Human Molecular Oncology Unit, Lille, France; Clinical Division of Oncology, Department of Medicine 1, CNS Unit Comprehensive Cancer Center Vienna (CCC-CNS), Vienna, Austria; Oscar Lambret Center, Biostatistic Unit, Lille, France; Medical University of Vienna, Vienna, Austria.
  • Weller M; Department of Neurology & Brain Tumor Center, University Hospital, Switzerland; University of Zurich, Switzerland. Electronic address: michael.weller@usz.ch.
  • Revillion F; Oscar Lambret Center, Human Molecular Oncology Unit, Lille, France; Clinical Division of Oncology, Department of Medicine 1, CNS Unit Comprehensive Cancer Center Vienna (CCC-CNS), Vienna, Austria. Electronic address: f-revillion@o-lambret.fr.
  • Bonneterre J; Univ. Lille, F-59000 Lille, France; Oscar Lambret Center, Medical Oncology Department, F-59000 Lille, France. Electronic address: j-bonneterre@o-lambret.fr.
Eur J Cancer ; 87: 189-198, 2017 12.
Article in En | MEDLINE | ID: mdl-29103666
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Biomarkers, Tumor / Central Nervous System Neoplasms / Polymorphism, Single Nucleotide / Proto-Oncogene Proteins c-akt / Phosphatidylinositol 3-Kinase / TOR Serine-Threonine Kinases Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Eur J Cancer Year: 2017 Document type: Article Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Breast Neoplasms / Biomarkers, Tumor / Central Nervous System Neoplasms / Polymorphism, Single Nucleotide / Proto-Oncogene Proteins c-akt / Phosphatidylinositol 3-Kinase / TOR Serine-Threonine Kinases Type of study: Diagnostic_studies / Etiology_studies / Prognostic_studies / Risk_factors_studies Limits: Adult / Aged / Female / Humans / Middle aged Language: En Journal: Eur J Cancer Year: 2017 Document type: Article Country of publication: United kingdom