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Knockout of the Arp2/3 complex in epidermis causes a psoriasis-like disease hallmarked by hyperactivation of transcription factor Nrf2.
van der Kammen, Rob; Song, Ji-Ying; de Rink, Iris; Janssen, Hans; Madonna, Stefania; Scarponi, Claudia; Albanesi, Cristina; Brugman, Wim; Innocenti, Metello.
Affiliation
  • van der Kammen R; Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, The Netherlands.
  • Song JY; Department of Experimental Animal Pathology, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • de Rink I; Genomics Core Facility, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • Janssen H; Division of Cell Biology II, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, The Netherlands.
  • Madonna S; Laboratory of Experimental Immunology, Fondazione Luigi Maria Monti - Istituto Dermopatico dell'Immacolata (IDI) - IRCCS, 00167 Rome, Italy.
  • Scarponi C; Laboratory of Experimental Immunology, Fondazione Luigi Maria Monti - Istituto Dermopatico dell'Immacolata (IDI) - IRCCS, 00167 Rome, Italy.
  • Albanesi C; Laboratory of Experimental Immunology, Fondazione Luigi Maria Monti - Istituto Dermopatico dell'Immacolata (IDI) - IRCCS, 00167 Rome, Italy.
  • Brugman W; Genomics Core Facility, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.
  • Innocenti M; Division of Molecular Genetics, The Netherlands Cancer Institute, Plesmanlaan 121, Amsterdam, 1066 CX, The Netherlands m.innocenti@nki.nl.
Development ; 144(24): 4588-4603, 2017 12 15.
Article in En | MEDLINE | ID: mdl-29113991
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psoriasis / Actin Cytoskeleton / Actins / Epidermis / Actin-Related Protein 2-3 Complex / NF-E2-Related Factor 2 Type of study: Etiology_studies / Prognostic_studies Limits: Adult / Animals / Female / Humans Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2017 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Psoriasis / Actin Cytoskeleton / Actins / Epidermis / Actin-Related Protein 2-3 Complex / NF-E2-Related Factor 2 Type of study: Etiology_studies / Prognostic_studies Limits: Adult / Animals / Female / Humans Language: En Journal: Development Journal subject: BIOLOGIA / EMBRIOLOGIA Year: 2017 Document type: Article Affiliation country: Netherlands Country of publication: United kingdom