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Inhibition of the NLRP3 inflammasome attenuates foam cell formation of THP-1 macrophages by suppressing ox-LDL uptake and promoting cholesterol efflux.
Chen, Liang; Yao, Qiying; Xu, Siwei; Wang, Hongyan; Qu, Peng.
Affiliation
  • Chen L; Department of Cardiology, Institute of Heart and Vascular Diseases, Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
  • Yao Q; Department of Physiology, School of Basic Medical Science, Dalian Medical University, Dalian, Liaoning, China.
  • Xu S; Department of Cardiology, Institute of Heart and Vascular Diseases, Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
  • Wang H; Department of Cardiology, Institute of Heart and Vascular Diseases, Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China.
  • Qu P; Department of Cardiology, Institute of Heart and Vascular Diseases, Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, China. Electronic address: qupeng7777@126.com.
Biochem Biophys Res Commun ; 495(1): 382-387, 2018 01 01.
Article in En | MEDLINE | ID: mdl-29122594
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholesterol / Inflammasomes / Foam Cells / NLR Family, Pyrin Domain-Containing 3 Protein / Lipoproteins, LDL / Macrophages Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2018 Document type: Article Affiliation country: China Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cholesterol / Inflammasomes / Foam Cells / NLR Family, Pyrin Domain-Containing 3 Protein / Lipoproteins, LDL / Macrophages Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2018 Document type: Article Affiliation country: China Country of publication: United States