Turning Over a New Leaf: Bacteriocins Going Green.

Ghequire, Maarten G K; De Mot, René

Ghequire, Maarten G K; De Mot, René.

Affiliation

Ghequire MGK; Centre of Microbial and Plant Genetics, KU Leuven, Kasteelpark Arenberg 20 box 2460, 3001 Heverlee, Belgium. Electronic address: maarten.ghequire@biw.kuleuven.be.
De Mot R; Centre of Microbial and Plant Genetics, KU Leuven, Kasteelpark Arenberg 20 box 2460, 3001 Heverlee, Belgium.

Trends Microbiol ; 26(1): 1-2, 2018 01.

Article in En | MEDLINE | ID: mdl-29150081

ABSTRACT

ABSTRACT

Bacteriocins are potent antibacterial proteins that selectively kill phylogenetic relatives of the producer. Their polymorphic nature, most prominent in Î³-Proteobacteria, offers potential for the design of customized bacteriocin cocktails targeting Gram-negative pathogens. As an alternative to recombinant production in bacteria, they are eligible for large-scale production in plants.

Subject(s)

Bacteriocins/metabolism; Plant Leaves/metabolism; Plants/metabolism; Anti-Bacterial Agents/metabolism; Anti-Bacterial Agents/pharmacology; Bacteriocins/classification; Bacteriocins/genetics; Bacteriocins/pharmacology; Colicins/metabolism; Gram-Negative Bacteria/drug effects; Plant Leaves/genetics; Plants/genetics; Protein Engineering; Pyocins/metabolism; Recombinant Proteins/biosynthesis

Key words

bacteriocin cocktail; colicin; plant-derived recombinant antimicrobials; protein engineering; pyocin

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plants / Bacteriocins / Plant Leaves Language: En Journal: Trends Microbiol Journal subject: MICROBIOLOGIA Year: 2018 Document type: Article

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