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The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia.
Di Tullio, Alessandro; Rouault-Pierre, Kevin; Abarrategi, Ander; Mian, Syed; Grey, William; Gribben, John; Stewart, Aengus; Blackwood, Elizabeth; Bonnet, Dominique.
Affiliation
  • Di Tullio A; Hematopoietic Stem Cell Laboratory, The Francis Crick Institute, 1 Midland Road, NW1 1AT, London, UK.
  • Rouault-Pierre K; Hematopoietic Stem Cell Laboratory, The Francis Crick Institute, 1 Midland Road, NW1 1AT, London, UK.
  • Abarrategi A; Department of Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, Chaterhouse Square, EC1M 6BQ, London, UK.
  • Mian S; Hematopoietic Stem Cell Laboratory, The Francis Crick Institute, 1 Midland Road, NW1 1AT, London, UK.
  • Grey W; Hematopoietic Stem Cell Laboratory, The Francis Crick Institute, 1 Midland Road, NW1 1AT, London, UK.
  • Gribben J; King's College London School of Medicine, Department of Haematological Medicine, The Rayne Institute, 123 Coldharbour Lane, SE5 9NU, London, UK.
  • Stewart A; Hematopoietic Stem Cell Laboratory, The Francis Crick Institute, 1 Midland Road, NW1 1AT, London, UK.
  • Blackwood E; Department of Haemato-Oncology, Barts Cancer Institute, Queen Mary University of London, Chaterhouse Square, EC1M 6BQ, London, UK.
  • Bonnet D; Bioinformatic Core, The Francis Crick Institute, 1 Midland Road, NW1 1AT, London, UK.
Nat Commun ; 8(1): 1679, 2017 11 22.
Article in En | MEDLINE | ID: mdl-29162833
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Pyridines / Pyrroles / Leukemia, Myeloid, Acute / Granulocyte Colony-Stimulating Factor / Cytarabine / Protein Kinase Inhibitors / Checkpoint Kinase 1 Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Pyridines / Pyrroles / Leukemia, Myeloid, Acute / Granulocyte Colony-Stimulating Factor / Cytarabine / Protein Kinase Inhibitors / Checkpoint Kinase 1 Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: Nat Commun Journal subject: BIOLOGIA / CIENCIA Year: 2017 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom