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Crosstalk between mAChRM3 and ß2AR, via acetylcholine PI3/PKC/PBEP1/Raf-1 MEK1/2/ERK1/2 pathway activation, in human bronchial epithelial cells after long-term cigarette smoke exposure.
Albano, Giusy Daniela; Bonanno, Anna; Moscato, Monica; Anzalone, Giulia; Di Sano, Caterina; Riccobono, Loredana; Wenzel, Sally E; Profita, Mirella.
Affiliation
  • Albano GD; Institute of Biomedicine and Molecular Immunology "A. Monroy" (IBIM), National Research Council of Italy (CNR), Palermo, Italy.
  • Bonanno A; Institute of Biomedicine and Molecular Immunology "A. Monroy" (IBIM), National Research Council of Italy (CNR), Palermo, Italy.
  • Moscato M; Institute of Biomedicine and Molecular Immunology "A. Monroy" (IBIM), National Research Council of Italy (CNR), Palermo, Italy.
  • Anzalone G; Institute of Biomedicine and Molecular Immunology "A. Monroy" (IBIM), National Research Council of Italy (CNR), Palermo, Italy.
  • Di Sano C; Institute of Biomedicine and Molecular Immunology "A. Monroy" (IBIM), National Research Council of Italy (CNR), Palermo, Italy.
  • Riccobono L; Institute of Biomedicine and Molecular Immunology "A. Monroy" (IBIM), National Research Council of Italy (CNR), Palermo, Italy.
  • Wenzel SE; University of Pittsburgh Asthma Institute at UPMC, Pulmonary, Allergy and Critical Care Medicine Division, University of Pittsburgh, United States.
  • Profita M; Institute of Biomedicine and Molecular Immunology "A. Monroy" (IBIM), National Research Council of Italy (CNR), Palermo, Italy. Electronic address: profita@ibim.cnr.it.
Life Sci ; 192: 99-109, 2018 Jan 01.
Article in En | MEDLINE | ID: mdl-29175450
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Smoke / Nicotiana / Bronchi / Signal Transduction / Smoking / Acetylcholine / Receptors, Adrenergic, beta-2 / Receptor Cross-Talk / Epithelial Cells / G-Protein-Coupled Receptor Kinase 2 Limits: Humans Language: En Journal: Life Sci Year: 2018 Document type: Article Affiliation country: Italy Country of publication: Netherlands
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Smoke / Nicotiana / Bronchi / Signal Transduction / Smoking / Acetylcholine / Receptors, Adrenergic, beta-2 / Receptor Cross-Talk / Epithelial Cells / G-Protein-Coupled Receptor Kinase 2 Limits: Humans Language: En Journal: Life Sci Year: 2018 Document type: Article Affiliation country: Italy Country of publication: Netherlands