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Xanthine-derived KMUP-1 reverses glucotoxicity-activated Kv channels through the cAMP/PKA signaling pathway in rat pancreatic ß cells.
Lee, Chien-Hsing; Chu, Chih-Sheng; Tsai, Han-Jie; Ke, Liang-Yin; Lee, Hsiang-Chun; Yeh, Jwu-Lai; Chen, Chu-Huang; Wu, Bin-Nan.
Affiliation
  • Lee CH; Department of Pharmacology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
  • Chu CS; Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan; Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
  • Tsai HJ; Department of Pharmacology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
  • Ke LY; Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Medical Laboratory Science and Biotechnology, College of Health Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
  • Lee HC; Division of Cardiology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan; Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
  • Yeh JL; Department of Pharmacology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.
  • Chen CH; Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Vascular and Medicinal Research, Texas Heart Institute, Houston, TX 77030, USA.
  • Wu BN; Department of Pharmacology, Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Lipid Science and Aging Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan; Department of Medical Research, Kaohsiung Medical University Hospital, K
Chem Biol Interact ; 279: 171-176, 2018 Jan 05.
Article in En | MEDLINE | ID: mdl-29183753

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Xanthines / Potassium Channels / Cyclic AMP-Dependent Protein Kinases / Cyclic AMP / Insulin-Secreting Cells / Glucose Limits: Animals Language: En Journal: Chem Biol Interact Year: 2018 Document type: Article Affiliation country: Taiwan

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Piperidines / Xanthines / Potassium Channels / Cyclic AMP-Dependent Protein Kinases / Cyclic AMP / Insulin-Secreting Cells / Glucose Limits: Animals Language: En Journal: Chem Biol Interact Year: 2018 Document type: Article Affiliation country: Taiwan