[Resection concepts for early stage neuroendocrine tumors of the lungs and bronchi]. / Resektionskonzepte bei frühen neuroendokrinen Tumoren der Lunge und Bronchien.

ABSTRACT

BACKGROUND: Neuroendocrine tumors of the lungs are a very inhomogeneous group of malignancies. The surgical treatment should be adapted to the anatomical localization and histological subtype and individualized according to the functional reserve. MATERIAL AND METHODS: We performed a selective review of current literature, which was supplemented by personal experiences. RESULTS: The currently available outcome data are very inhomogeneous and depend on the histological subtype of neuroendocrine pulmonary tumors. A radical R0 resection is the key for an improvement in long-term overall and disease-free survival. CONCLUSION: Surgical treatment of carcinoid tumors is the current standard therapy. Sleeve resection should be performed, whenever possible. More aggressive tumors, such as large cell neuroendocrine carcinoma and small cell lung cancer should be treated in a multimodal concept.