Crystalline arthropathy and bone health.
Curr Opin Rheumatol
; 30(2): 173-176, 2018 03.
Article
in En
| MEDLINE
| ID: mdl-29194109
ABSTRACT
PURPOSE OF REVIEW The purpose of this review is to provide insight on the proposed association between crystal arthritis and bone health. Crystal arthritis is the most common type of inflammatory arthritis, and fractures contribute to significant morbidity and mortality, therefore, the relationship between the two is of clinical importance. RECENT FINDINGS:
There have been variable findings regarding hyperuricemia, low bone density and risk of fracture. A recent systematic review and meta-analysis of available literature showed a correlation between increased serum uric acid and lower risk of fracture. Less is known about calcium pyrophosphate deposition disease and bone health, although two large studies have suggested an association with osteopenia.SUMMARY:
A systematic review and meta-analysis of available data suggest a correlation between increased serum uric acid and lower risk of fracture. Findings support an association between bone health and crystal arthritis which warrants further study and may have implications for how we treat gout.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Bone and Bones
/
Bone Density
/
Fractures, Bone
/
Crystal Arthropathies
Type of study:
Systematic_reviews
Limits:
Humans
Language:
En
Journal:
Curr Opin Rheumatol
Journal subject:
REUMATOLOGIA
Year:
2018
Document type:
Article
Affiliation country:
United States