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Diversity of Nicotinic Acetylcholine Receptor Positive Allosteric Modulators Revealed by Mutagenesis and a Revised Structural Model.
Newcombe, Joseph; Chatzidaki, Anna; Sheppard, Tom D; Topf, Maya; Millar, Neil S.
Affiliation
  • Newcombe J; Departments of Chemistry (J.N., T.D.S.) and Neuroscience, Physiology and Pharmacology (A.C., N.S.M.), University College London, London, United Kingdom; and Institute of Structural and Molecular Biology, Birkbeck, University of London, London, United Kingdom (J.N., M.T.).
  • Chatzidaki A; Departments of Chemistry (J.N., T.D.S.) and Neuroscience, Physiology and Pharmacology (A.C., N.S.M.), University College London, London, United Kingdom; and Institute of Structural and Molecular Biology, Birkbeck, University of London, London, United Kingdom (J.N., M.T.).
  • Sheppard TD; Departments of Chemistry (J.N., T.D.S.) and Neuroscience, Physiology and Pharmacology (A.C., N.S.M.), University College London, London, United Kingdom; and Institute of Structural and Molecular Biology, Birkbeck, University of London, London, United Kingdom (J.N., M.T.).
  • Topf M; Departments of Chemistry (J.N., T.D.S.) and Neuroscience, Physiology and Pharmacology (A.C., N.S.M.), University College London, London, United Kingdom; and Institute of Structural and Molecular Biology, Birkbeck, University of London, London, United Kingdom (J.N., M.T.) n.millar@ucl.ac.uk m.topf@cr
  • Millar NS; Departments of Chemistry (J.N., T.D.S.) and Neuroscience, Physiology and Pharmacology (A.C., N.S.M.), University College London, London, United Kingdom; and Institute of Structural and Molecular Biology, Birkbeck, University of London, London, United Kingdom (J.N., M.T.) n.millar@ucl.ac.uk m.topf@cr
Mol Pharmacol ; 93(2): 128-140, 2018 02.
Article in En | MEDLINE | ID: mdl-29196491
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Quinolines / Sulfonamides / Nicotinic Agonists / Alpha7 Nicotinic Acetylcholine Receptor / Naphthalenes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Pharmacol Year: 2018 Document type: Article Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrroles / Quinolines / Sulfonamides / Nicotinic Agonists / Alpha7 Nicotinic Acetylcholine Receptor / Naphthalenes Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Pharmacol Year: 2018 Document type: Article Country of publication: United States