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Salidroside attenuates hypoxia-induced pulmonary arterial smooth muscle cell proliferation and apoptosis resistance by upregulating autophagy through the AMPK-mTOR-ULK1 pathway.
Gui, Di; Cui, Zhimin; Zhang, Lin; Yu, Chang; Yao, Dan; Xu, Min; Chen, Mayun; Wu, Peiliang; Li, Guoping; Wang, Liangxing; Huang, Xiaoying.
Affiliation
  • Gui D; Division of Pulmonary Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang, 325000, People's Republic of China.
  • Cui Z; Division of Pulmonary Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang, 325000, People's Republic of China.
  • Zhang L; Division of Pulmonary Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang, 325000, People's Republic of China.
  • Yu C; Department of Invasive Technology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325000, People's Republic of China.
  • Yao D; Division of Pulmonary Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang, 325000, People's Republic of China.
  • Xu M; Division of Pulmonary Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang, 325000, People's Republic of China.
  • Chen M; Division of Pulmonary Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang, 325000, People's Republic of China.
  • Wu P; Division of Pulmonary Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang, 325000, People's Republic of China.
  • Li G; Department of Respiratory Medicine, Tongde Hospital of Zhejiang Province, Hangzhou, Zhejiang, 310013, People's Republic of China.
  • Wang L; Division of Pulmonary Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang, 325000, People's Republic of China. wzyxywlx@163.com.
  • Huang X; Division of Pulmonary Medicine, The First Affiliated Hospital of Wenzhou Medical University, Key Laboratory of Heart and Lung, Wenzhou, Zhejiang, 325000, People's Republic of China. zjwzhxy@126.com.
BMC Pulm Med ; 17(1): 191, 2017 Dec 12.
Article in En | MEDLINE | ID: mdl-29233105
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocytes, Smooth Muscle / Cell Proliferation / AMP-Activated Protein Kinases / Autophagy-Related Protein-1 Homolog / Hypoxia Limits: Animals Language: En Journal: BMC Pulm Med Year: 2017 Document type: Article Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Myocytes, Smooth Muscle / Cell Proliferation / AMP-Activated Protein Kinases / Autophagy-Related Protein-1 Homolog / Hypoxia Limits: Animals Language: En Journal: BMC Pulm Med Year: 2017 Document type: Article Country of publication: United kingdom