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Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury.
Magnaghi, Paola; Salom, Barbara; Cozzi, Liviana; Amboldi, Nadia; Ballinari, Dario; Tamborini, Elena; Gasparri, Fabio; Montagnoli, Alessia; Raddrizzani, Laura; Somaschini, Alessio; Bosotti, Roberta; Orrenius, Christian; Bozzi, Fabio; Pilotti, Silvana; Galvani, Arturo; Sommer, Josh; Stacchiotti, Silvia; Isacchi, Antonella.
Affiliation
  • Magnaghi P; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy. paola.magnaghi@nervianoms.com.
  • Salom B; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
  • Cozzi L; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
  • Amboldi N; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
  • Ballinari D; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
  • Tamborini E; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Gasparri F; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
  • Montagnoli A; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
  • Raddrizzani L; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
  • Somaschini A; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
  • Bosotti R; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
  • Orrenius C; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
  • Bozzi F; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Pilotti S; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Galvani A; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
  • Sommer J; Chordoma Foundation, Durham, North Carolina.
  • Stacchiotti S; Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Isacchi A; Oncology, Nerviano Medical Sciences, Nerviano, Milan, Italy.
Mol Cancer Ther ; 17(3): 603-613, 2018 03.
Article in En | MEDLINE | ID: mdl-29237806
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Neoplasms / Chordoma / T-Box Domain Proteins / Xenograft Model Antitumor Assays / Fetal Proteins / ErbB Receptors / Afatinib Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2018 Document type: Article Affiliation country: Italy Country of publication: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bone Neoplasms / Chordoma / T-Box Domain Proteins / Xenograft Model Antitumor Assays / Fetal Proteins / ErbB Receptors / Afatinib Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Mol Cancer Ther Journal subject: ANTINEOPLASICOS Year: 2018 Document type: Article Affiliation country: Italy Country of publication: United States