Curcumin regulates intracellular calcium release and inhibits oxidative stress parameters, VEGF, and caspase-3/-9 levels in human retinal pigment epithelium cells.

Bardak, H; Uguz, A C; Bardak, Y

Bardak, H; Uguz, A C; Bardak, Y.

Affiliation

Bardak H; 1 Department of Ophthalmology, Haydarpasa Numune Research and Training Hospital , Istanbul, Turkey.
Uguz AC; 2 Faculty of Medicine, Department of Biophysics, Süleyman Demirel University , Isparta, Turkey.
Bardak Y; 3 Neuroscience Research Center, Süleyman Demirel University , Isparta, Turkey.

Physiol Int ; 104(4): 301-315, 2017 Dec 01.

Article in En | MEDLINE | ID: mdl-29278024

Subject(s)

Calcium Signaling/physiology; Caspase 3/metabolism; Caspase 9/metabolism; Curcumin/administration & dosage; Retinal Pigment Epithelium/physiology; Vascular Endothelial Growth Factor A/metabolism; Vision, Ocular/physiology; Calcium Signaling/drug effects; Calcium Signaling/radiation effects; Cell Line; Dose-Response Relationship, Drug; Humans; Light; Oxidative Stress/physiology; Oxidative Stress/radiation effects; Reactive Oxygen Species/metabolism; Retinal Pigment Epithelium/drug effects; Retinal Pigment Epithelium/radiation effects; Vision, Ocular/drug effects; Vision, Ocular/radiation effects

Key words

ARPE-19 cells; Ca2+ signaling; apoptosis; blue light damage; curcumin; oxidative stress

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vision, Ocular / Calcium Signaling / Curcumin / Vascular Endothelial Growth Factor A / Caspase 3 / Caspase 9 / Retinal Pigment Epithelium Type of study: Prognostic_studies Limits: Humans Language: En Journal: Physiol Int Year: 2017 Document type: Article Affiliation country: Turkey Country of publication: Hungary

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google