Animal models of excessive aggression: implications for human aggression and violence.
Curr Opin Psychol
; 19: 81-87, 2018 02.
Article
in En
| MEDLINE
| ID: mdl-29279228
ABSTRACT
Escalated interpersonal aggression and violence are common symptoms of multiple psychiatric disorders and represent a significant global health issue. Current therapeutic strategies are limited due to a lack of understanding about the neural and molecular mechanisms underlying the 'vicious' shift of normal adaptive aggression into violence, and the environmental triggers that cause it. Development of novel animal models that validly capture the salient features of human violent actions combined with newly emerging technologies for mapping, measuring, and manipulating neuronal activity in the brain significantly advance our understanding of the etiology, neuromolecular mechanisms, and potential therapeutic interventions of excessive aggressive behaviors in humans.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Violence
/
Models, Animal
/
Aggression
Type of study:
Diagnostic_studies
Aspects:
Determinantes_sociais_saude
Limits:
Animals
/
Humans
Language:
En
Journal:
Curr Opin Psychol
Year:
2018
Document type:
Article