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Hsp70 Inhibits the Nucleation and Elongation of Tau and Sequesters Tau Aggregates with High Affinity.
Kundel, Franziska; De, Suman; Flagmeier, Patrick; Horrocks, Mathew H; Kjaergaard, Magnus; Shammas, Sarah L; Jackson, Sophie E; Dobson, Christopher M; Klenerman, David.
Affiliation
  • Kundel F; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • De S; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Flagmeier P; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Horrocks MH; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Kjaergaard M; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Shammas SL; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Jackson SE; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Dobson CM; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
  • Klenerman D; Department of Chemistry , University of Cambridge , Lensfield Road , Cambridge CB2 1EW , United Kingdom.
ACS Chem Biol ; 13(3): 636-646, 2018 03 16.
Article in En | MEDLINE | ID: mdl-29300447
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / HSP70 Heat-Shock Proteins / Protein Aggregation, Pathological Limits: Humans Language: En Journal: ACS Chem Biol Year: 2018 Document type: Article Affiliation country: United kingdom
Fulltext
Add to My VHL
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Tau Proteins / HSP70 Heat-Shock Proteins / Protein Aggregation, Pathological Limits: Humans Language: En Journal: ACS Chem Biol Year: 2018 Document type: Article Affiliation country: United kingdom