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A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial.
Hanratty, Catherine E; Matthews, John G; Arron, Joseph R; Choy, David F; Pavord, Ian D; Bradding, P; Brightling, Christopher E; Chaudhuri, Rekha; Cowan, Douglas C; Djukanovic, Ratko; Gallagher, Nicola; Fowler, Stephen J; Hardman, Tim C; Harrison, Tim; Holweg, Cécile T; Howarth, Peter H; Lordan, James; Mansur, Adel H; Menzies-Gow, Andrew; Mosesova, Sofia; Niven, Robert M; Robinson, Douglas S; Shaw, Dominick E; Walker, Samantha; Woodcock, Ashley; Heaney, Liam G.
Affiliation
  • Hanratty CE; Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University, Belfast, UK. c.hanratty@qub.ac.uk.
  • Matthews JG; Genentech Inc., South San Francisco, California, USA.
  • Arron JR; Genentech Inc., South San Francisco, California, USA.
  • Choy DF; Genentech Inc., South San Francisco, California, USA.
  • Pavord ID; Nuffield Department of Medicine, The University of Oxford, Oxford, UK.
  • Bradding P; Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Leicester, UK.
  • Brightling CE; Department of Infection, Immunity and Inflammation, Institute for Lung Health, University of Leicester, Leicester, UK.
  • Chaudhuri R; Greater Glasgow Health Board, Glasgow, UK.
  • Cowan DC; NHS Greater Glasgow and Clyde, Stobhill Hospital, Glasgow, UK.
  • Djukanovic R; Academic Unit of Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
  • Gallagher N; Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University, Belfast, UK.
  • Fowler SJ; Division of Infection, Immunity and Respiratory Medicine, University of Manchester, Manchester, UK.
  • Hardman TC; Niche Science & Technology Unit 26, Falstaff House, Bardolph Road, Richmond, TW9 2LH, UK.
  • Harrison T; University of Nottingham, Nottingham, UK.
  • Holweg CT; Genentech Inc., South San Francisco, California, USA.
  • Howarth PH; University of Southampton, Centre for Inflammation, Infection and Repair, Southampton, UK.
  • Lordan J; The Newcastle upon Tyne NHS Foundation Trust, Newcastle upon Tyne, UK.
  • Mansur AH; University of Birmingham and Heartlands Hospital, Heart of England NHS Foundation Trust, Birmingham, UK.
  • Menzies-Gow A; Royal Brompton & Harefield NHS Foundation Trust, London, UK.
  • Mosesova S; Genentech Inc., South San Francisco, California, USA.
  • Niven RM; Institute of Inflammation and Repair, The University of Manchester, Manchester, UK.
  • Robinson DS; University College Hospitals NHS Foundation Trust, London, UK.
  • Shaw DE; University of Nottingham, Nottingham, UK.
  • Walker S; Asthma, 18 Mansell Street, London, E1 8AA, UK.
  • Woodcock A; University College Hospitals NHS Foundation Trust, London, UK.
  • Heaney LG; Centre for Experimental Medicine, School of Medicine, Dentistry and Biomedical Sciences, Queen's University, Belfast, UK.
Trials ; 19(1): 5, 2018 Jan 04.
Article in En | MEDLINE | ID: mdl-29301585
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Adrenal Cortex Hormones / Drug Dosage Calculations / Lung Type of study: Clinical_trials / Diagnostic_studies / Guideline / Prognostic_studies Aspects: Patient_preference Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Trials Journal subject: MEDICINA / TERAPEUTICA Year: 2018 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Asthma / Adrenal Cortex Hormones / Drug Dosage Calculations / Lung Type of study: Clinical_trials / Diagnostic_studies / Guideline / Prognostic_studies Aspects: Patient_preference Limits: Adolescent / Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: En Journal: Trials Journal subject: MEDICINA / TERAPEUTICA Year: 2018 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom