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Design and Synthesis of A-Ring Simplified Pyripyropene A Analogues as Potent and Selective Synthetic SOAT2 Inhibitors.
Ohtawa, Masaki; Arima, Shiho; Ichida, Naoki; Terayama, Tomiaki; Ohno, Hironao; Yamazaki, Takaya; Ohshiro, Taichi; Sato, Noriko; Omura, Satoshi; Tomoda, Hiroshi; Nagamitsu, Tohru.
Affiliation
  • Ohtawa M; Department of Synthetic Natural Products Chemistry, School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Arima S; Department of Synthetic Natural Products Chemistry, School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Ichida N; Department of Synthetic Natural Products Chemistry, School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Terayama T; Department of Synthetic Natural Products Chemistry, School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Ohno H; Department of Synthetic Natural Products Chemistry, School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Yamazaki T; Department of Synthetic Natural Products Chemistry, School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Ohshiro T; Department of Microbial Chemistry, School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Sato N; School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Omura S; Kitasato Institute for Life Sciences and Graduate School of Infection Control Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Tomoda H; Department of Microbial Chemistry, School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
  • Nagamitsu T; Department of Synthetic Natural Products Chemistry, School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
ChemMedChem ; 13(5): 411-421, 2018 03 06.
Article in En | MEDLINE | ID: mdl-29323466
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Sesquiterpenes / Drug Design / Sterol O-Acyltransferase / Enzyme Inhibitors Limits: Animals Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2018 Document type: Article Affiliation country: Japan Country of publication: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Sesquiterpenes / Drug Design / Sterol O-Acyltransferase / Enzyme Inhibitors Limits: Animals Language: En Journal: ChemMedChem Journal subject: FARMACOLOGIA / QUIMICA Year: 2018 Document type: Article Affiliation country: Japan Country of publication: Germany