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Wee1 inhibitor MK1775 sensitizes KRAS mutated NSCLC cells to sorafenib.
Caiola, Elisa; Frapolli, Roberta; Tomanelli, Michele; Valerio, Rossana; Iezzi, Alice; Garassino, Marina C; Broggini, Massimo; Marabese, Mirko.
Affiliation
  • Caiola E; Laboratory of Molecular Pharmacology, Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
  • Frapolli R; Laboratory of Cancer Pharmacology, Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
  • Tomanelli M; Laboratory of Molecular Pharmacology, Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
  • Valerio R; Laboratory of Molecular Pharmacology, Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
  • Iezzi A; Laboratory of Molecular Pharmacology, Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
  • Garassino MC; Thoracic Oncology Unit, Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.
  • Broggini M; Laboratory of Molecular Pharmacology, Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy.
  • Marabese M; Laboratory of Molecular Pharmacology, Department of Oncology, IRCCS - Istituto di Ricerche Farmacologiche "Mario Negri", Milan, Italy. mirko.marabese@marionegri.it.
Sci Rep ; 8(1): 948, 2018 01 17.
Article in En | MEDLINE | ID: mdl-29343688
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylurea Compounds / Pyrazoles / Pyrimidines / Protein-Tyrosine Kinases / Nuclear Proteins / Proto-Oncogene Proteins p21(ras) / Niacinamide / Carcinoma, Non-Small-Cell Lung / Cell Cycle Proteins / Lung Neoplasms Limits: Humans Language: En Journal: Sci Rep Year: 2018 Document type: Article Affiliation country: Italy Country of publication: United kingdom
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Phenylurea Compounds / Pyrazoles / Pyrimidines / Protein-Tyrosine Kinases / Nuclear Proteins / Proto-Oncogene Proteins p21(ras) / Niacinamide / Carcinoma, Non-Small-Cell Lung / Cell Cycle Proteins / Lung Neoplasms Limits: Humans Language: En Journal: Sci Rep Year: 2018 Document type: Article Affiliation country: Italy Country of publication: United kingdom