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Plasmodium dihydrofolate reductase is a second enzyme target for the antimalarial action of triclosan.
Bilsland, Elizabeth; van Vliet, Liisa; Williams, Kevin; Feltham, Jack; Carrasco, Marta P; Fotoran, Wesley L; Cubillos, Eliana F G; Wunderlich, Gerhard; Grøtli, Morten; Hollfelder, Florian; Jackson, Victoria; King, Ross D; Oliver, Stephen G.
Affiliation
  • Bilsland E; Cambridge Systems Biology Centre & Department of Biochemistry, University of Cambridge, Cambridge, UK.
  • van Vliet L; Department of Structural and Functional Biology, Institute of Biology, UNICAMP, Campinas, SP, Brazil.
  • Williams K; Cambridge Systems Biology Centre & Department of Biochemistry, University of Cambridge, Cambridge, UK.
  • Feltham J; Department of Computer Science, Aberystwyth University, Aberystwyth, UK.
  • Carrasco MP; Cambridge Systems Biology Centre & Department of Biochemistry, University of Cambridge, Cambridge, UK.
  • Fotoran WL; Department of Chemistry & Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
  • Cubillos EFG; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
  • Wunderlich G; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
  • Grøtli M; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, SP, Brazil.
  • Hollfelder F; Department of Chemistry & Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
  • Jackson V; Cambridge Systems Biology Centre & Department of Biochemistry, University of Cambridge, Cambridge, UK.
  • King RD; Manchester Institute of Biotechnology, University of Manchester, Manchester, UK.
  • Oliver SG; Manchester Institute of Biotechnology, University of Manchester, Manchester, UK.
Sci Rep ; 8(1): 1038, 2018 01 18.
Article in En | MEDLINE | ID: mdl-29348637
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium / Tetrahydrofolate Dehydrogenase / Triclosan / Folic Acid Antagonists / Antimalarials Language: En Journal: Sci Rep Year: 2018 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom
Fulltext
Add to My VHL
Print
XML
PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium / Tetrahydrofolate Dehydrogenase / Triclosan / Folic Acid Antagonists / Antimalarials Language: En Journal: Sci Rep Year: 2018 Document type: Article Affiliation country: United kingdom Country of publication: United kingdom